PROTECTIVE EFFICACY OF PERTACTIN CONTAINING ACELLULAR DPT VACCINES

<em>Pertussis vaccination with the use of DPT vaccines is a necessary condition for fighting the infection called bordetella pertussis. At the same time, it is known that the use of whole cellular DPT vaccines is accompanied with high incidence of side effects and serious neurological complica...

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Main Authors: M.V. Fesenko (Author), L.S. Namazova (Author)
Format: Book
Published: "Paediatrician" Publishers LLC, 2008-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a M.V. Fesenko  |e author 
700 1 0 |a L.S. Namazova  |e author 
245 0 0 |a PROTECTIVE EFFICACY OF PERTACTIN CONTAINING ACELLULAR DPT VACCINES 
260 |b "Paediatrician" Publishers LLC,   |c 2008-01-01T00:00:00Z. 
500 |a 1682-5527 
500 |a 1682-5535 
520 |a <em>Pertussis vaccination with the use of DPT vaccines is a necessary condition for fighting the infection called bordetella pertussis. At the same time, it is known that the use of whole cellular DPT vaccines is accompanied with high incidence of side effects and serious neurological complications, and, as a result, reasonable refuse from injections by the population. Creation of less reactogenic, acellular vaccines would not only permit to decrease the incidence of side effects, but also increase the efficiency of pertussis vaccination. Maximum protective effect is achieved by using threebcomponent vaccines ( 80%), containng pertactin - outer membrane protein b. pertussis. the absence of this antigen in twobcomponent DPT vaccines predetermines their significantly lower efficacy.</em><br /><strong><em>Key words: children, pertussis, acellular DPT vaccines, pertactin. </em></strong> 
546 |a EN 
546 |a RU 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Вопросы современной педиатрии, Vol 7, Iss 2, Pp 77-81 (2008) 
787 0 |n http://vsp.spr-journal.ru:80/jour/article/view/1372 
787 0 |n https://doaj.org/toc/1682-5527 
787 0 |n https://doaj.org/toc/1682-5535 
856 4 1 |u https://doaj.org/article/ed8a750f0a904ebca46aaf89da3a6465  |z Connect to this object online.