Safety and efficacy of a freeze-dried trivalent antivenom for snakebites in the Brazilian Amazon: An open randomized controlled phase IIb clinical trial.

• Main Authors: Iran Mendonça- (Author), Antônio Magela Tavares (Author), Jacqueline Sachett (Author), José Felipe Sardinha (Author), Lilian Zaparolli (Author), Maria Fátima Gomes Santos (Author), Marcus Lacerda (Author), Wuelton Marcelo Monteiro (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In tropical areas, a major concern regarding snakebites treatment effectiveness relates to the failure in liquid antivenom (AV) distribution due to the lack of an adequate cold chain in remote areas. To minimize this problem, freeze-drying has been suggested to improve AV stability.This study compar...