A novel synthetic DNA vaccine elicits protective immune responses against Powassan virus.

• Main Authors: Hyeree Choi (Author), Sagar B Kudchodkar (Author), Michelle Ho (Author), Emma L Reuschel (Author), Erin Reynolds (Author), Ziyang Xu (Author), Devivasha Bordoloi (Author), Kenneth E Ugen (Author), Pablo Tebas (Author), Joseph Kim (Author), Mohamed Abdel-Mohsen (Author), Saravanan Thangamani (Author), David B Weiner (Author), Kar Muthumani (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Powassan virus (POWV) infection is a tick-borne emerging infectious disease in the United States and North America. Like Zika virus, POWV is a member of the family Flaviviridae. POWV causes severe neurological sequalae, meningitis, encephalitis, and can cause death. Although the risk of human POWV i...