Synthesis of Novel (<i>S</i>)-3-(1-Aminoethyl)-8-pyrimidinyl-2-phenylisoquinolin-1(2<i>H</i>)-ones by Suzuki-Miyaura Coupling and Their Cell Toxicity Activities

• Main Authors: Ok Kyoung Choi (Author), Yong Ho Sun (Author), Hyemi Lee (Author), Joon Kwang Lee (Author), Tae Hoon Lee (Author), Hakwon Kim (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of (<i>S</i>)-3-(1-aminoethyl)-8-pyrimidinyl-2-phenylisoquinoline-1(2<i>H</i>)-ones <b>3a</b>-<b>3k</b> was synthesized in 40-98% yield through Suzuki-Miyaura coupling using Pd(PPh₃)₂Cl<sub>2...