Engineering chromosome rearrangements in cancer

• Main Authors: Salvador Alonso (Author), Lukas E. Dow (Author)
• Formato: Libro
• Publicado: The Company of Biologists, 2021-09-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

The identification of large chromosomal rearrangements in cancers has multiplied exponentially over the last decade. These complex and often rare genomic events have traditionally been challenging to study, in part owing to lack of tools that efficiently engineer disease-associated inversions, delet...