Assessing Lymphatic Uptake of Lipids Using Magnetic Resonance Imaging: A Feasibility Study in Healthy Human Volunteers with Potential Application for Tracking Lymph Node Delivery of Drugs and Formulation Excipients

• Main Authors: Adelaide Jewell (Author), Hannah Williams (Author), Caroline L. Hoad (Author), Paul R. Gellert (Author), Marianne B. Ashford (Author), James Butler (Author), Snow Stolnik (Author), David Scurr (Author), Michael J. Stocks (Author), Luca Marciani (Author), Penny A. Gowland (Author), Pavel Gershkovich (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dietary lipids and some pharmaceutical lipid excipients can facilitate the targeted delivery of drugs to the intestinal lymphatics. Here, the feasibility of magnetic resonance imaging (MRI) for imaging lipid uptake into the intestinal lymphatics was assessed, shedding light on which lymph nodes can...