Recent Advances in Covalent Drug Discovery

• প্রধান লেখক: Daniel Schaefer (Author), Xinlai Cheng (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2023-04-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

In spite of the increasing number of biologics license applications, the development of covalent inhibitors is still a growing field within drug discovery. The successful approval of some covalent protein kinase inhibitors, such as ibrutinib (BTK covalent inhibitor) and dacomitinib (EGFR covalent in...