Genetically-engineered "all-in-one" vaccine platform for cancer immunotherapy

• Main Authors: Aihua Wu (Author), Yingzhi Chen (Author), Hairui Wang (Author), Ya Chang (Author), Meng Zhang (Author), Pengfei Zhao (Author), Yisi Tang (Author), Qin Xu (Author), Zhuangzhi Zhu (Author), Yang Cao (Author), Yongzhuo Huang (Author)
• Format: Book
• Published: Elsevier, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

An essential step for cancer vaccination is to break the immunosuppression and elicit a tumor-specific immunity. A major hurdle against cancer therapeutic vaccination is the insufficient immune stimulation of the cancer vaccines and lack of a safe and efficient adjuvant for human use. We discovered...