Down regulating PHGDH affects the lactate production of sertoli cells in varicocele

• Main Authors: Wen-bin Guo (Author), Zhen-hui Huang (Author), Cheng Yang (Author), Xian-yuan Lv (Author), Hui Xia (Author), Hu Tian (Author), Jian-kun Yang (Author), Qi-zhao Zhou (Author), Ming-kun Chen (Author), Kang-yi Xue (Author), Cun-dong Liu (Author)
• Format: Book
• Published: BMC, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Although varicocele is considered to be one of the leading causes of male infertility, the precise mechanism underlying how varicocele leads to male infertility is not completely understood. We found the lactate concentration on the varicocele side of the patients was decreased c...