Dihydroberberine alleviates Th17/Treg imbalance in premature ovarian insufficiency mice via inhibiting Rheb/mTOR signaling

• Egile Nagusiak: Disi Deng (Egilea), Yeke Wu (Egilea), Keming Wu (Egilea), Nan Zeng (Egilea), Wanjing Li (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2024-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background Premature ovarian insufficiency (POI) is an immune-related condition. Dihydroberberine (dhBBR) plays a regulatory role in maintaining the T-helper 17 (Th17)/regulatory T (Treg) cell balance. This study aimed to explore the action mechanisms of dhBBR on POI. Methods In vivo, femal...