Quantifying Radiosensitization of PSMA-Targeted Gold Nanoparticles on Prostate Cancer Cells at Megavoltage Radiation Energies by Monte Carlo Simulation and Local Effect Model

• Main Authors: Ryder M. Schmidt (Author), Daiki Hara (Author), Jorge D. Vega (Author), Marwan B. Abuhaija (Author), Wensi Tao (Author), Nesrin Dogan (Author), Alan Pollack (Author), John C. Ford (Author), Junwei Shi (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Active targeting gold nanoparticles (AuNPs) are a very promising avenue for cancer treatment with many publications on AuNP mediated radiosensitization at kilovoltage (kV) photon energies. However, uncertainty on the effectiveness of AuNPs under clinically relevant megavoltage (MV) radiation energie...