Population Pharmacokinetics of Cyclosporine in Chinese Pediatric Patients With Acquired Aplastic Anemia

• Main Authors: Xuan Gao (Author), Zhu-Li Bian (Author), Xiao-Hong Qiao (Author), Xiao-Wen Qian (Author), Jun Li (Author), Guo-Mei Shen (Author), Hui Miao (Author), Yi Yu (Author), Jian-Hua Meng (Author), Xiao-Hua Zhu (Author), Jun-Ye Jiang (Author), Jun Le (Author), Ling Yu (Author), Hong-Sheng Wang (Author), Xiao-Wen Zhai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cyclosporine (CsA) is a component of the first-line treatment for acquired aplastic anemia (acquired AA) in pediatric patients. This study aimed to develop a population pharmacokinetic (PK) model of CsA in Chinese pediatric patients with acquired AA to inform individual dosage regimens. A total of 6...