PPAR-γ Agonist GW1929 Targeted to Macrophages with Dendrimer-Graphene Nanostars Reduces Liver Fibrosis and Inflammation

• Main Authors: Alazne Moreno-Lanceta (Author), Mireia Medrano-Bosch (Author), Blanca Simón-Codina (Author), Montserrat Barber-González (Author), Wladimiro Jiménez (Author), Pedro Melgar-Lesmes (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macrophages play essential roles during the progression of chronic liver disease. They actively participate in the response to liver damage and in the balance between fibrogenesis and regression. The activation of the PPARγ nuclear receptor in macrophages has traditionally been associated with an an...