Identification of novel indole derivatives acting as inhibitors of the Keap1-Nrf2 interaction

Nine indole derivatives (9a-i) were tested as potential inhibitors of the Keap1-Nrf2 interaction. This class of compounds increases the intracellular levels of the transcription factor Nrf2 and the consequent expression of enzymes encoded by genes containing the antioxidant response element (ARE). I...

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Main Authors: Barbara Cosimelli (Author), Giovanni Greco (Author), Sonia Laneri (Author), Ettore Novellino (Author), Antonia Sacchi (Author), Giorgio Amendola (Author), Sandro Cosconati (Author), Roberta Bortolozzi (Author), Giampietro Viola (Author)
Format: Book
Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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