Anti-Tumor Activity of Orally Administered Gefitinib-Loaded Nanosized Cubosomes against Colon Cancer

• Main Authors: Ahmed A. El-Shenawy (Author), Mahmoud M. A. Elsayed (Author), Gamal M. K. Atwa (Author), Mohammed A. S. Abourehab (Author), Mohamed S. Mohamed (Author), Mohammed M. Ghoneim (Author), Reda A. Mahmoud (Author), Shereen A. Sabry (Author), Walid Anwar (Author), Mohamed El-Sherbiny (Author), Yasser A. Hassan (Author), Amany Belal (Author), Abd El hakim Ramadan (Author)
• Formato: Libro
• Publicado: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Gefitinib (GFT) is a tyrosine kinase inhibitor drug used as a first-line treatment for patients with advanced or metastatic non-small cell lung, colon, and breast cancer. GFT exhibits low solubility and hence low oral bioavailability, which restricts its clinical application. One of the most importa...