Fabrication and Characterization of Tedizolid Phosphate Nanocrystals for Topical Ocular Application: Improved Solubilization and In Vitro Drug Release

• Main Authors: Mohd Abul Kalam (Author), Muzaffar Iqbal (Author), Abdullah Alshememry (Author), Musaed Alkholief (Author), Aws Alshamsan (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Positively charged NCs of TZP (0.1%, <i>w</i>/<i>v</i>) for ocular use were prepared by the antisolvent precipitation method. TZP is a novel 5-Hydroxymethyl-Oxazolidinone class of antibiotic and is effective against many drug-resistant bacterial infections. Even the phosphate...