Effective quantitative real-time polymerase chain reaction analysis of the parkin gene (<it>PARK2</it>) exon 1-12 dosage

• Main Authors: Ivanova-Smolenskaia Irina I (Author), Illarioshkin Sergei N (Author), Bagyeva Gulbahar H (Author), Slominsky Petr A (Author), Semenova Elena V (Author), Shadrina Maria I (Author), Limborska Svetlana A (Author)
• Format: Book
• Published: BMC, 2007-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>One of the causes of Parkinson's disease is mutations in the <it>PARK2 </it>gene. Deletions and duplications of single exons or exon groups account for a large proportion of the gene mutations. Direct detection of th...