Fibroblast growth factor 2 modulates extracellular purine metabolism by upregulating ecto-5'-nucleotidase and adenosine deaminase in cultured rat spinal cord astrocytes

• Principais autores: Ryota Eguchi (Autor), Soichiro Yamaguchi (Autor), Ken-ichi Otsuguro (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2019-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Purinergic signaling via ATP and adenosine produced by astrocytes is one pathway underlying neuron-glia interactions in the central nervous system (CNS). In production of purines, extracellular metabolism of released purines via ecto-enzymes is important. The expression and activities of these enzym...