Detection of large deletions in the LDL receptor gene with quantitative PCR methods

• Main Authors: Larsen Mogens L (Author), Stenderup Anette (Author), Nielsen Gitte G (Author), Jensen Lillian G (Author), Nissen Peter H (Author), Damgaard Dorte (Author), Faergeman Ole (Author)
• Format: Book
• Published: BMC, 2005-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Familial Hypercholesterolemia (FH) is a common genetic disease and at the molecular level most often due to mutations in the LDL receptor gene. In genetically heterogeneous populations, major structural rearrangements account for abo...