Pravastatin Attenuates Acute Radiation-Induced Enteropathy and Improves Epithelial Cell Function

• Main Authors: Hyosun Jang (Author), Janet Lee (Author), Sunhoo Park (Author), Hyunwook Myung (Author), Jihoon Kang (Author), Kyuchang Kim (Author), Hyewon Kim (Author), Won-Suk Jang (Author), Sun-Joo Lee (Author), Sehwan Shim (Author), Jae K. Myung (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Aim: Radiation-induced enteropathy is frequently observed after radiation therapy for abdominal and pelvic cancer or occurs secondary to accidental radiation exposure. The acute effects of irradiation on the intestine might be attributed to inhibition of mitosis in the crypts, as the...