Notoginsenoside R1 Ameliorates Cardiac Lipotoxicity Through AMPK Signaling Pathway

• Main Authors: Xue Tian (Author), Xu Chen (Author), Qianqian Jiang (Author), Qianbin Sun (Author), Tiantian Liu (Author), Yiqin Hong (Author), Yawen Zhang (Author), Yanyan Jiang (Author), Mingyan Shao (Author), Ran Yang (Author), Chun Li (Author), Qiyan Wang (Author), Yong Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: Cardiac lipotoxicity is the common consequence of lipid metabolism disorders in cardiomyocytes during development of heart failure (HF). Adenosine 5'monophosphate-activated protein kinase (AMPK) acts as an energy sensor and has a beneficial effect in reducing lipotoxicity. Notoginsenoside...