Patchoulene Epoxide Isolated from Patchouli Oil Suppresses Acute Inflammation through Inhibition of NF-κB and Downregulation of COX-2/iNOS

• Main Authors: Jia-Li Liang (Author), Jia-Zhen Wu (Author), Yu-Hong Liu (Author), Zhen-Biao Zhang (Author), Qi-Duan Wu (Author), Han-Bin Chen (Author), Yan-Feng Huang (Author), Yao-Xing Dou (Author), Jiang-Tao Zhou (Author), Zi-Ren Su (Author), Janis Ya-Xian Zhan (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

According to the GC-MS analysis, compositional variation was observed between samples of patchouli oil, of which an unknown compound identified as patchoulene epoxide (PAO) was found only in the long-stored oil, whose biological activity still remains unknown. Therefore, the present study aimed to e...