Intravenous Administration of Coenzyme Q10 in Acute Period of Cerebral Ischemia Decreases Mortality by Reducing Brain Necrosis and Limiting Its Increase within 4 Days in Rat Stroke Model

• Päätekijät: Olga N. Obolenskaia (Tekijä), Evgeniya A. Gorodetskaya (Tekijä), Elena I. Kalenikova (Tekijä), Margarita A. Belousova (Tekijä), Mikhail V. Gulyaev (Tekijä), Valery G. Makarov (Tekijä), Yury A. Pirogov (Tekijä), Oleg S. Medvedev (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2020-12-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Oxidative stress plays a key role in the pathogenesis of ischemic stroke. Coenzyme Q10 has a multi-targeting effect and may protect the brain against ischemic damage. The aim of our study was to evaluate the neuroprotective potential of ubiquinol by its intravenous administration. The study was perf...