Population Pharmacokinetic/Pharmacodynamic Modeling of Depot Testosterone Cypionate in Healthy Male Subjects

• Autori principali: Youwei Bi (Autore), Paul J. Perry (Autore), Michael Ellerby (Autore), Daryl J. Murry (Autore)
• Natura: Libro
• Pubblicazione: Wiley, 2018-04-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

A randomized, double‐blind clinical trial was conducted to investigate long‐term abuse effects of testosterone cypionate (TC). Thirty‐one healthy men were randomized into a dose group of 100, 250, or 500 mg/wk and received 14 weekly injections of TC. A pharmacokinetic/pharmacodynamic (PK/PD) model w...