Epigenetic Control of Macrophage Polarisation and Soluble Mediator Gene Expression during Inflammation

• Main Authors: Theodore S. Kapellos (Author), Asif J. Iqbal (Author)
• Formato: Livro
• Publicado em: Hindawi Limited, 2016-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Macrophages function as sentinel cells, which constantly monitor the host environment for infection or injury. Macrophages have been shown to exhibit a spectrum of activated phenotypes, which can often be categorised under the M1/M2 paradigm. M1 macrophages secrete proinflammatory cytokines and chem...