The Balance of MU-Opioid, Dopamine D2 and Adenosine A2A Heteroreceptor Complexes in the Ventral Striatal-Pallidal GABA Antireward Neurons May Have a Significant Role in Morphine and Cocaine Use Disorders

• Autores principales: Dasiel O. Borroto-Escuela (Autor), Karolina Wydra (Autor), Ramon Fores-Pons (Autor), Lakshmi Vasudevan (Autor), Wilber Romero-Fernandez (Autor), Małgorzata Frankowska (Autor), Luca Ferraro (Autor), Sarah Beggiato (Autor), Minerva Crespo-Ramirez (Autor), Alicia Rivera (Autor), Luisa L. Rocha (Autor), Miguel Perez de la Mora (Autor), Christophe Stove (Autor), Małgorzata Filip (Autor), Kjell Fuxe (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The widespread distribution of heteroreceptor complexes with allosteric receptor-receptor interactions in the CNS represents a novel integrative molecular mechanism in the plasma membrane of neurons and glial cells. It was proposed that they form the molecular basis for learning and short-and long-t...