In vitro and ex vivo antiplasmodial activity of 1-(3-benzyloxy-4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-propan-1-one) against circulating strains of Plasmodium spp. in the state of Rondônia, Brazil

• Main Authors: Vanessa Margarida Vicentini (Author), Welington da Silva Paula do Nascimento (Author), Marcinete Latorre Almeida (Author), Daniel Sol Sol de Medeiros (Author), Ana Paula de Azevedo dos Santos (Author), Joana D 'Arc Neves Costa (Author), Dhélio Batista Pereira (Author), Mauro Shugiro Tada (Author), Leonardo de Azevedo Calderon (Author), Carolina Bioni Garcia Teles (Author)
• Format: Book
• Published: Universidade de São Paulo, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Malaria is a disease caused by Plasmodium spp. protozoa. The ability of Plasmodium to develop resistance to current antimalarial drugs makes the study of chemotherapeutic alternatives extremely important. This study aimed to evaluate the antimalarial activity of compound 3286938 (1-(3-benzy...