Regulatory T cells in the pathogenesis and healing of chronic human dermal leishmaniasis caused by Leishmania (Viannia) species.

• Main Authors: Daniel Rodriguez-Pinto (Author), Adriana Navas (Author), Víctor Manuel Blanco (Author), Lady Ramírez (Author), Daniel Garcerant (Author), Adriana Cruz (Author), Noah Craft (Author), Nancy Gore Saravia (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The inflammatory response is prominent in the pathogenesis of dermal leishmaniasis. We hypothesized that regulatory T cells (Tregs) may be diminished in chronic dermal leishmaniasis (CDL) and contribute to healing during treatment.The frequency and functional capacity of Tregs were evaluated at diag...