Eosinophil-expressed galectin-3 regulates cell trafficking and migration

• Main Authors: Xiao Na eGe (Author), Sung Gil eHa (Author), Fu-Tong eLiu (Author), Savita P Rao (Author), P eSriramarao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2013-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Galectin-3 (Gal-3), a β galactoside-binding lectin, is implicated in the pathogenesis of allergic airway inflammation and allergen-challenged mice deficient in Gal-3 (Gal-3-/-) exhibit decreased airway recruitment of eosinophils (Eos). Gal-3 is expressed and secreted by several cell types and can th...