Nanohydrogels Based on Self-Assembly of Cationic Pullulan and Anionic Dextran Derivatives for Efficient Delivery of Piroxicam

• Main Authors: Dorota Lachowicz (Author), Przemyslaw Mielczarek (Author), Roma Wirecka (Author), Katarzyna Berent (Author), Anna Karewicz (Author), Michał Szuwarzyński (Author), Szczepan Zapotoczny (Author)
• Format: Book
• Published: MDPI AG, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A cationic derivative of pullulan was obtained by grafting reaction and used together with dextran sulfate to form polysaccharide-based nanohydrogel cross-linked via electrostatic interactions between polyions. Due to the polycation-polyanion interactions nanohydrogel particles were formed instantly...