Artificial Protein Coronas Enable Controlled Interaction with Corneal Epithelial Cells: New Opportunities for Ocular Drug Delivery

• Main Authors: Carlo Astarita (Author), Sara Palchetti (Author), Mina Massaro-Giordano (Author), Marina Di Domenico (Author), Francesco Petrillo (Author), Silvia Boffo (Author), Giulio Caracciolo (Author), Antonio Giordano (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Topical administration is the most convenient route for ocular drug delivery, but only a minor fraction is retained in the precorneal pocket. To overcome this limitation, numerous drug delivery systems (DDS) have been developed. The protein corona (PC) is the layer of biomolecules (e.g., proteins, s...