Eggshell membrane modulates gut microbiota to prevent murine pre‐cachexia through suppression of T helper cell differentiation

• Main Authors: Huijuan Jia (Author), Weida Lyu (Author), Kazuki Hirota (Author), Eri Saito (Author), Moe Miyoshi (Author), Hirohiko Hohjoh (Author), Kyohei Furukawa (Author), Kenji Saito (Author), Makoto Haritani (Author), Akashi Taguchi (Author), Yukio Hasebe (Author), Hisanori Kato (Author)
• Format: Book
• Published: Wiley, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cachexia is a life‐threatening condition observed in several pathologies, such as cancer or chronic diseases. Interleukin 10 (Il10) gene transfer is known to improve cachexia by downregulating Il6. Here, we used an IL10‐knockout mouse model to simulate cachexia and investigate th...