Cross-serotypically conserved epitope recommendations for a universal T cell-based dengue vaccine.

• Main Authors: Syed Faraz Ahmed (Author), Ahmed A Quadeer (Author), John P Barton (Author), Matthew R McKay (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue virus (DENV)-associated disease is a growing threat to public health across the globe. Co-circulating as four different serotypes, DENV poses a unique challenge for vaccine design as immunity to one serotype predisposes a person to severe and potentially lethal disease upon infection from oth...