Analyzing Alkyl Bromide Genotoxic Impurities in Febuxostat Based on Static Headspace Sampling and GC-ECD

Analyzing Alkyl Bromide Genotoxic Impurities in Febuxostat Based on Static Headspace Sampling and GC-ECD

Herein, a sensitive and selective gas chromatography-electron capture detector (GC-ECD) method was developed and validated for the quantification of trace levels of five bromo-containing genotoxic impurities in Febuxostat active pharmaceutical ingredient (API) after headspace sampling (HS). Multivar...

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Main Authors: Alexandros Kavrentzos (Author), Elli Vastardi (Author), Evangelos Karavas (Author), Paraskevas D. Tzanavaras (Author), Constantinos K. Zacharis (Author)
Format: Book
Published: MDPI AG, 2024-03-01T00:00:00Z.
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