Oridonin attenuates low shear stress-induced endothelial cell dysfunction and oxidative stress by activating the nuclear factor erythroid 2-related factor 2 pathway

• Main Authors: Zhipeng Chen (Author), Heqian Liu (Author), Xiaoqi Zhao (Author), Subinur Mamateli (Author), Cheng Liu (Author), Lei Wang (Author), Jing Yu (Author), Yutong Liu (Author), Jing Cai (Author), Tong Qiao (Author)
• Format: Book
• Published: BMC, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Atherosclerosis (AS) is the primary cause of cardiovascular disease and the incidence is extremely common; however, there are currently few drugs that can effectively treat AS. Although oridonin has been widely used to treat inflammation and cancer for numerous years, to the best...