SDF-1/CXCR4 Axis Promotes MSCs to Repair Liver Injury Partially through Trans-Differentiation and Fusion with Hepatocytes

• Главные авторы: Ning-Bo Hao (Автор), Chang-Zhu Li (Автор), Mu-Han Lü (Автор), Bo Tang (Автор), Su-Min Wang (Автор), Yu-Yun Wu (Автор), Guang-Ping Liang (Автор), Shi-Ming Yang (Автор)
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• Опубликовано: Hindawi Limited, 2015-01-01T00:00:00Z.
• Предметы: article
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MSCs have become a popular target for developing end-stage liver therapies. In this study, two models of bone marrow chimeric mice were used to construct the liver failure models. Then it was found that MSCs can transdifferentiate into hepatocyte-like cells and these hepatocyte-like cells can signif...