Forskolin rapidly enhances neuron‐like morphological change of directly induced‐neuronal cells from neurofibromatosis type 1 patients

• Main Authors: Noriaki Sagata (Author), Shin‐ichi Kano (Author), Masahiro Ohgidani (Author), Shogo Inamine (Author), Yasunari Sakai (Author), Hiroki Kato (Author), Keiji Masuda (Author), Takeshi Nakahara (Author), Makiko Nakahara‐Kido (Author), Shouichi Ohga (Author), Masutaka Furue (Author), Akira Sawa (Author), Shigenobu Kanba (Author), Takahiro A. Kato (Author)
• Format: Book
• Published: Wiley, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Aim Neurofibromatosis type 1 (NF1) is a multifaceted disease, and frequently comorbid with neurodevelopmental disorders such as autism spectrum disorder (ASD) and learning disorder. Dysfunction of adenylyl cyclase (AC) is one of the candidate pathways in abnormal development of neuronal cel...