Antioxidant Response in Human X-Linked Adrenoleukodystrophy Fibroblasts

• Autors principals: Sara Petrillo (Autor), Jessica D'Amico (Autor), Francesco Nicita (Autor), Caterina Torda (Autor), Gessica Vasco (Autor), Enrico S. Bertini (Autor), Marco Cappa (Autor), Fiorella Piemonte (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2022-10-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Redox imbalance, mitochondrial dysfunction, and inflammation play a major role in the pathophysiology of X-linked adrenoleukodystrophy (X-ALD), an inherited neurodegenerative disease caused by mutations in the ABCD1 gene, encoding the protein responsible for peroxisomal import and degradation of ver...