Inhibition of SARS-CoV-2-Induced NLRP3 Inflammasome-Mediated Lung Cell Inflammation by Triphala-Loaded Nanoparticle Targeting Spike Glycoprotein S1

• Main Authors: Chuda Chittasupho (Author), Sonthaya Umsumarng (Author), Kamonwan Srisawad (Author), Punnida Arjsri (Author), Rungsinee Phongpradist (Author), Weerasak Samee (Author), Wipawan Tingya (Author), Chadarat Ampasavate (Author), Pornngarm Dejkriengkraikul (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The COVID-19 pandemic, caused by SARS-CoV-2, poses a significant global health threat. The spike glycoprotein S1 of the SARS-CoV-2 virus is known to induce the production of pro-inflammatory mediators, contributing to hyperinflammation in COVID-19 patients. Triphala, an ancient Ayurvedic remedy comp...