Discovery of Therapeutics Targeting Oxidative Stress in Autosomal Recessive Cerebellar Ataxia: A Systematic Review

• Main Authors: Sze Yuen Lew (Author), Michael Weng Lok Phang (Author), Pit Shan Chong (Author), Jaydeep Roy (Author), Chi Him Poon (Author), Wing Shan Yu (Author), Lee Wei Lim (Author), Kah Hui Wong (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Autosomal recessive cerebellar ataxias (ARCAs) are a heterogeneous group of rare neurodegenerative inherited disorders. The resulting motor incoordination and progressive functional disabilities lead to reduced lifespan. There is currently no cure for ARCAs, likely attributed to the lack of understa...