Toll-Like Receptor 4: A Promising Therapeutic Target for Alzheimer's Disease

• Main Authors: Linyu Wu (Author), Xiaohui Xian (Author), Guangyu Xu (Author), Zixuan Tan (Author), Fang Dong (Author), Min Zhang (Author), Feng Zhang (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alzheimer's disease (AD) is a progressive neurodegenerative disease that primarily manifests as memory deficits and cognitive impairment and has created health challenges for patients and society. In AD, amyloid β-protein (Aβ) induces Toll-like receptor 4 (TLR4) activation in microglia. Activat...