Design, synthesis and in vitro biological studies of novel triazoles with potent and broad-spectrum antifungal activity

• Main Authors: Junhe Bao (Author), Yumeng Hao (Author), Tingjunhong Ni (Author), Ruina Wang (Author), Jiacun Liu (Author), Xiaochen Chi (Author), Ting Wang (Author), Shichong Yu (Author), Yongsheng Jin (Author), Lan Yan (Author), Xiaomei Li (Author), Dazhi Zhang (Author), Fei Xie (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of novel triazole derivatives containing aryl-propanamide side chains was designed and synthesised. In vitro antifungal activity studies demonstrated that most of the compounds inhibited the growth of six human pathogenic fungi. In particular, parts of phenyl-propionamide-containing compoun...