Design, synthesis and evaluation of cytotoxic, antimicrobial, and anti-HIV-1 activities of new 1,2,3,4-tetrahydropyrimidine derivatives

• Main Authors: Nima Razzaghi-Asl (Author), Mahsa Kamrani-Moghadam (Author), Behzad Farhangi (Author), Rouhollah Vahabpour (Author), Rezvan Zabihollahi (Author), Saghi Sepehri (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of new 1,2,3,4-tetrahydropyrimidine (THPM) derivatives were designed and synthesized within a one-pot three component Biginelli reaction. The structures of compounds were characterized by FT-IR, 1H- NMR, mass spectroscopy, and elemental analysis. All synthesized derivatives were screened fo...