Design, synthesis and evaluation of cytotoxic, antimicrobial, and anti-HIV-1 activities of new 1,2,3,4-tetrahydropyrimidine derivatives

• मुख्य लेखकों: Nima Razzaghi-Asl (लेखक), Mahsa Kamrani-Moghadam (लेखक), Behzad Farhangi (लेखक), Rouhollah Vahabpour (लेखक), Rezvan Zabihollahi (लेखक), Saghi Sepehri (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wolters Kluwer Medknow Publications, 2019-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

A series of new 1,2,3,4-tetrahydropyrimidine (THPM) derivatives were designed and synthesized within a one-pot three component Biginelli reaction. The structures of compounds were characterized by FT-IR, 1H- NMR, mass spectroscopy, and elemental analysis. All synthesized derivatives were screened fo...