Understanding peroral absorption: regulatory aspects and contemporary approaches to tackling solubility and permeability hurdles

• Главные авторы: Prachi B. Shekhawat (Автор), Varsha B. Pokharkar (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2017-05-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Oral drug absorption is a process influenced by the physicochemical and biopharmaceutical properties of the drug and its inter-relationship with the gastrointestinal tract. Drug solubility, dissolution and permeability across intestinal barrier are the key parameters controlling absorption. This rev...