Regulation of receptor interacting protein kinase 1-mediated apoptosis by cordycepin attenuated hypoxia/reoxygenation-induced renal tubular epithelial cell injury

• Main Authors: Xiu-tao Han (Author), Xiu-zhao Fan (Author), Zhi-bo Zhao (Author), Jing-yu Zhao (Author), Jun-hu Li (Author), Fang Zhang (Author), Gai-ying Jiang (Author), Li-jun Zhang (Author), Fa-hui Chen (Author), Meng-qi Bai (Author), Xiao-shuang Zhou (Author)
• Format: Book
• Published: Editorial Department of Journal of Clinical Nephrology, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective To explore the therapeutic mechanism of cordycepin for acute kidney injury （AKI） based upon gene chips in gene expression omnibus （GEO） database, network pharmacology, molecular docking and in vitro experiments. Methods Targeted genes of AKI were obtained from two databases, GEO （GSE87025）...