Caffeine Therapy for Apnea of Prematurity: Role of the Circadian CLOCK Gene Polymorphism

• Main Authors: Hong-Li Guo (Author), Jia-Yi Long (Author), Ya-Hui Hu (Author), Yun Liu (Author), Xin He (Author), Ling Li (Author), Ying Xia (Author), Xuan-Sheng Ding (Author), Feng Chen (Author), Jing Xu (Author), Rui Cheng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Standard-dose caffeine citrate has been routinely prescribed for apnea of prematurity (AOP) management; however, some preterm infants respond well to the therapy while others do not. The AOP phenotype has been attributed solely to the immature control of the respiratory system consequent to preterm...