The antidiabetic effect of methanolic extract of Holarrhena pubescens seeds is mediated through multiple mechanisms of action

• Main Authors: AbdulRahman A I Alyahya (Author), Mohammed Asad (Author), Mohammed Sanad Alhussaini (Author), Kamal Eldin Ahmed Abdelsalam (Author), Essa Awad Alenezi (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Holarrhena pubescens is widely used in Indian and Chinese medicine in the treatment of diabetes. The current work determined the oral hypoglycemic and antidiabetic effects of seed extract in rats. The probable mechanism of action was evaluated in-vitro by α - glucosidase inhibition, glucose metaboli...