Sphingosine 1-phosphate protects against radiation-induced ovarian injury in female rats-impact on mitochondrial-related genes

• Main Authors: Jiahui Zhao (Author), Shuyun Zhang (Author), Liesong Chen (Author), Xiaolong Liu (Author), Haihong Su (Author), Lili Chen (Author), Li Yang (Author), Hong Zhang (Author)
• Format: Book
• Published: BMC, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The toxic effects of ionizing radiation on the gonads have been widely recognized. Sphingosine 1-phosphate (S1P) has a protective effect on ovarian injury, and although it is known that mitochondria are involved in this process, the specific mechanism is not fully understood. The present st...