Prolonged fasting drives a program of metabolic inflammation in human adipose tissue

• Main Authors: Pouneh K. Fazeli (Author), Yang Zhang (Author), John O'Keefe (Author), Tristan Pesaresi (Author), Mingyue Lun (Author), Brian Lawney (Author), Matthew L. Steinhauser (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The human adaptive fasting response enables survival during periods of caloric deprivation. A crucial component of the fasting response is the shift from glucose metabolism to utilization of lipids, underscoring the importance of adipose tissue as the central lipid-storing organ. The obje...